Tanner Stage Summary Data
Here we present the summary data from the genome-wide meta-analysis of Tanner Stage, a measure of sexual maturation, in subjects of European ancestry. These data include directly genotyped SNPs and SNPs imputed against the HapMap CEU data (release 22).
Phenotypes and Data
Tanner stage data on male genital development and female breast development were run separately and combined. Please see the publication for more details on each phenotype. To ensure high quality data, only SNPs for which 90% of samples were successful are included. P-values are corrected for genomic inflation.
|Phenotype||Description||Maximum N||Downloadable file|
|TANNER males||Tanner male genital stage at age 12.6-15 yrs||3,769||EGG_TANNER_males.v2.txt.gz|
|TANNER females||Tanner female breast stage at age 10.5 - 12.5 yrs||6,147||EGG_TANNER_females.v2.txt.gz|
|TANNER males and females combined||Tanner male genital stage and female breast stage combined||9,916||EGG_TANNER_males_and_females_combined.v2.txt.gz|
Acknowledging The Data
When using data from the downloadable meta-analyses results please acknowledge the source of the data as follows:
Data on Tanner pubertal development stage has been contributed by the EGG Consortium and was downloaded from www.egg-consortium.org.
In addition to the above acknowledgement, please cite the paper below:
Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty.
Hum Molec Genet. 2014 Aug 15;23(16):4452-64.